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Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity
Chuanfeng Wu, Cynthia E. Dunbar
Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 356-371 doi: 10.1007/s11684-011-0159-1
Keywords: gene therapy hematopoietic stem cells insertional mutagenesis genotoxicity induced pluripotent stem cell
Adoptive cell transfer therapy for hepatocellular carcinoma
Renyu Zhang, Zhao Zhang, Zekun Liu, Ding Wei, Xiaodong Wu, Huijie Bian, Zhinan Chen
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 3-11 doi: 10.1007/s11684-019-0684-x
Keywords: adoptive cell transfer therapy hepatocellular carcinoma T cell chimeric antigen receptor immunotherapy
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 827-858 doi: 10.1007/s11684-022-0948-8
Keywords: infertility stem cell therapy mesenchymal stem cells pluripotent stem cells
Molecular markers and pathogenically targeted therapy in non-small cell lung cancer
Bo PENG BA , Jinnong ZHANG MD , Jamile S. WOODS MD , Wei PENG MD, PhD
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 245-255 doi: 10.1007/s11684-009-0044-3
Keywords: lung cancer carcinoma non-small cell lung cancer molecular markers targeted therapy
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 711-725 doi: 10.1007/s11684-020-0808-3
Keywords: chimeric antigen receptor T (CAR-T) cell lymphoma cytokine release syndrome (CRS) immune effector cell-associated
Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 766-772 doi: 10.1007/s11684-021-0916-8
Keywords: anlotinib chemotherapy short-term relapsed small-cell lung cancer
Chemical transdifferentiation: closer to regenerative medicine
Aining Xu,Lin Cheng
Frontiers of Medicine 2016, Volume 10, Issue 2, Pages 152-165 doi: 10.1007/s11684-016-0445-z
Cell transdifferentiation, which directly switches one type of differentiated cells into another celltype, is more advantageous than cell reprogramming to generate pluripotent cells and differentiate themdevelopments in the research of small molecules in promoting cell conversion.Particularly, we focus on the complete chemical compound-induced cell transdifferentiation, which iscloser to the clinical translation in cell therapy.
Keywords: cell therapy cell transdifferentiation chemical compounds small molecules tissue regeneration
Precision medicine in acute lymphoblastic leukemia
Ching-Hon Pui
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 689-700 doi: 10.1007/s11684-020-0759-8
Keywords: acute lymphoblastic leukemia molecular therapeutics targeted therapy tyrosine kinase inhibitors immunotherapy CAR T-cell therapy
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 815-826 doi: 10.1007/s11684-021-0891-0
Keywords: B-cell lymphoma oral drug targeted therapy immunotherapy COVID-19 pandemic
The regulatory sciences for stem cell-based medicinal products
Bao-Zhu Yuan,Junzhi Wang
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 190-200 doi: 10.1007/s11684-014-0323-5
Over the past few years, several new achievements have been made from stem cell studies, many of whichMoreover, some stem cell-based products have been approved for marketing by different national regulatoryHowever, many critical issues associated mainly with incomplete understanding of stem cell biology andIn this review, we summarize some new achievements in stem cell studies, especially the preclinical andabreast of evolvement of stem cell sciences and technologies.
Keywords: stem cell-based medicinal products (SCMPs) stem cell therapy (SCT) safety effectiveness standards guidelines
Ping Li, Ningxin Dong, Yu Zeng, Jie Liu, Xiaochen Tang, Junbang Wang, Wenjun Zhang, Shiguang Ye, Lili Zhou, Alex Hongsheng Chang, Aibin Liang
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 811-815 doi: 10.1007/s11684-020-0740-6
Keywords: anti-CD19 chimeric antigen receptor T cells mantle cell lymphoma relapsed or refractory long-term follow-up
NADPH oxidase and reactive oxygen species as signaling molecules in carcinogenesis
Gang WANG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 1-7 doi: 10.1007/s11684-009-0018-5
Keywords: free radicals tumor phox cell proliferation cancer therapy
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 784-798 doi: 10.1007/s11684-021-0911-0
Keywords: uveal melanoma mutant GNAQ/11 palmitoylation BCL2 combination target therapy
Cell Therapy: Pharmacological Intervention Enters a Third Era
Wei He
Engineering 2019, Volume 5, Issue 1, Pages 5-9 doi: 10.1016/j.eng.2018.11.017
Title Author Date Type Operation
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity
Chuanfeng Wu, Cynthia E. Dunbar
Journal Article
Adoptive cell transfer therapy for hepatocellular carcinoma
Renyu Zhang, Zhao Zhang, Zekun Liu, Ding Wei, Xiaodong Wu, Huijie Bian, Zhinan Chen
Journal Article
Cell therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism
Journal Article
Molecular markers and pathogenically targeted therapy in non-small cell lung cancer
Bo PENG BA , Jinnong ZHANG MD , Jamile S. WOODS MD , Wei PENG MD, PhD
Journal Article
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Journal Article
Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup
Journal Article
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
Journal Article
Gu Zhen: Cell Loading Device for Cell Therapy (2022-7-24)
27 Jul 2022
Conference Videos
The regulatory sciences for stem cell-based medicinal products
Bao-Zhu Yuan,Junzhi Wang
Journal Article
Chimeric antigen receptor T-cell therapy: a promising treatment modality for relapsed/refractory mantlecell lymphoma
Ping Li, Ningxin Dong, Yu Zeng, Jie Liu, Xiaochen Tang, Junbang Wang, Wenjun Zhang, Shiguang Ye, Lili Zhou, Alex Hongsheng Chang, Aibin Liang
Journal Article
NADPH oxidase and reactive oxygen species as signaling molecules in carcinogenesis
Gang WANG
Journal Article
Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal
Journal Article